Psilocybin molecule:

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Psilocybin Clinical Trials

Exploratory Study of the Effects of Low-Dose Psilocybin on Sensory Processing, Neurophysiological Arousal, and Emotional Health

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Id: NCT05227742

Organisation Name: University of Alabama at Birmingham

Overal Status: Not yet recruiting

Start Date: March 2023

Last Update: January 9, 2023

Lead Sponsor: University of Alabama at Birmingham

Brief Summary: The purpose of the present study is to evaluate the feasibility, initial signals of efficacy, and potential mechanisms of action of "microdoses" of psilocybin (i.e., low doses of psilocybin that are not believed to produce mystical-type, transcendent, hallucinogenic, or other overtly salient subjective effects that limit functionality) in the treatment of moderate to severe demoralization (feelings of hopelessness and meaningless that frequently accompany medical illness and other life hardship).

  • Demoralization

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