Psilocybin molecule:

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Psilocybin Clinical Trials

Safety and Efficacy of Psilocybin for the Treatment of Headache Disorders: Sub-Study II

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Id: NCT03806985

Organisation Name: Yale University

Overal Status: Recruiting

Start Date: March 28, 2019

Last Update: July 28, 2022

Lead Sponsor: Yale University

Brief Summary: The purpose of this study is to investigate the effects of oral psilocybin in post-traumatic headache. Subjects will be randomized to receive placebo, low dose psilocybin, or high dose psilocybin on two separate test days approximately 14 days apart. Subjects will maintain a headache diary prior to, during, and after the treatments in order to document headache frequency and intensity, as well as associated symptoms. Blood samples will be drawn at various timepoints to measure levels of inflammatory peptides.

  • Post-Traumatic Headache

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