Psilocybin molecule:

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Psilocybin Clinical Trials

Safety and Efficacy of Psilocybin for the Treatment of Headache Disorders: Sub-Study I

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Id: NCT03341689

Organisation Name: Yale University

Overal Status: Active, not recruiting

Start Date: November 1, 2017

Last Update: February 25, 2022

Lead Sponsor: Yale University

Brief Summary: The purpose of this study is to investigate the effects of oral psilocybin in migraine headache. Subjects will each receive a dose of placebo and a dose of psilocybin approximately 14 days apart. Subjects will be randomized to the order of treatment and they will be randomized to receive either low or high dose psilocybin. Subjects will maintain a headache diary prior to, during, and after the treatments in order to document headache frequency and intensity, as well as associated symptoms. This preliminary study will inform on the basic effects of psilocybin in migraine headache and inform on the design of larger, more definitive studies.

  • Migraine Headache

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