Psilocybin molecule:

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Psilocybin Clinical Trials

The Neurobiological Effect of 5-HT2AR Modulation

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Id: NCT03289949

Organisation Name: Rigshospitalet, Denmark

Overal Status: Recruiting

Start Date: March 3, 2017

Last Update: August 16, 2022

Lead Sponsor: Gitte Moos Knudsen

Brief Summary: The investigators wish to investigate neurobiological effects of serotonin 2A receptor modulation in healthy volunteers, contrasting effects of an agonist (psilocybin) and an antagonist (ketanserin). Magnetic resonance imaging (MRI) and positron emission tomography (PET) will be used as neuroimaging tools.

  • Basic Science

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