Mdma molecule:

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Mdma Clinical Trials


MDMA and memory.


To see complete record on www.trialregister.nl, please visit this link

Id: NTR1416

Organisation Name: Dr J.G.Ramaekers Dept of Neuropsychology & Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University. Email: j.ramaekers@psychology.unimaas.nl

Overal Status: Stopped, trial finished

Start Date: 2005-08-01

Lead Sponsor: Dr J.G.Ramaekers Dept of Neuropsychology & Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University. Email: j.ramaekers@psychology.unimaas.nl

Brief Summary: Prospective memory refers to the realization of delayed intentions and is an ability that is at the heart of goal directed behavior in everyday life. A number of studies have shown that MDMA users perform worse on subjective and objective measures of prospective memory as compared to non drug using controls. Interpretation of these data however may be limited due to polydrug use, psychosocial stressors and increased psychopathology that have been reported in MDMA users. The present study was designed to directly assess the pharmacological effect of MDMA on prospective memory and brain activity in a double-blind, placebo controlled, cross-over study. Twelve recreational MDMA users received MDMA 75mg and placebo and performed an objective prospective memory task during functional imaging in a 3 Tesla MR scanner.

The present study was expected to provide:

1. direct evidence for the association between MDMA and memory impairment;

2. objective assessments of prospective memory function during MDMA intoxication;

3. neural structures critically involved in memory dysfunction during MDMA intoxication.

Country: Netherlands



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