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Mdma Clinical Trials

Exploring Mechanisms of Action of ±3,4-methylenedioxymethamphetamine (MDMA)- Assisted Psychotherapy for Posttraumatic Stress Disorder (PTSD)

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Id: NCT02102802

Organisation Name: Multidisciplinary Association for Psychedelic Studies

Overal Status: Completed

Start Date: January 2014

Last Update: June 21, 2022

Lead Sponsor: Multidisciplinary Association for Psychedelic Studies

Brief Summary: This study measures biological and psychological processes that might help researchers to better understand what is taking place during low or medium dose and full dose MDMA-assisted psychotherapy treatment in people with PTSD. Heart rate variability (HRV) will be measured up to three times; before and once or twice after receiving MDMA-assisted psychotherapy. Brain activity will be measured before and after MDMA-assisted psychotherapy in response to personalized trauma-related scripts. Participants will complete a measure of self-compassion at baseline and two months after a final experimental treatment session. Therapy techniques observed during recorded treatment sessions will be classified using a standardized clinical measure.

  • Posttraumatic Stress Disorder

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