Ketamine molecule:

Image from PubChem

Ketamine Clinical Trials


The NorKet Study


To see complete record on www.trialregister.nl, please visit this link

Id: NTR1328

Organisation Name: Leiden University Medical Center (LUMC), Department of Anaesthesiology

Overal Status: Planned

Start Date: 2008-08-01

Lead Sponsor: Leiden University Medical Center (LUMC), Department of Anaesthesiology

Brief Summary: The analgesic effects of S(+)-ketamine are known. S(+)-ketamine effects neurocognition. The contribution of its metabolite is however not known. With this study we are inducing the metabolism of S(+)-ketamine into norketamine. Heat pain is induced in healthy male volunteers, and VAS pain score will be obtained at the same time as blood samples are taken for pk/pd analysis. Also neurocognition is tested.

Country: Netherlands



Total execution time in seconds: 0.056738138198853