Ketamine molecule:

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Ketamine Clinical Trials

Neuroprotective Effects of ACTH4-10PRO8-GLY9-PRO10 on The Ketamine-Induced Neurotoxicity In Neonatal Rats: Increased BDNF Expression And BDNF Serum Concentrations

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Id: NCT05648526

Organisation Name: Universitas Sumatera Utara

Overal Status: Completed

Start Date: August 1, 2021

Last Update: December 13, 2022

Lead Sponsor: Universitas Sumatera Utara

Brief Summary: The compound ACTH4-10Pro8-Gly9-Pro10 is a synthetic analog molecule of an adrenocorticotropic hormone (ACTH) short fragment. That is free from hormonal effects and has neuromodulatory effects. We investigate the neuroprotective effects of ACTH4-10Pro8-Gly9-Pro10 can lessen neurotoxicity against ketamine in neonatal rats by looking at BDNF expression in the cortex and hippocampus tissue as well as BDNF blood levels.

  • Ketamine-Induced Neurotoxicity

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