Ketamine molecule:

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Ketamine Clinical Trials

KetaMoHydBup: Pharmacokinetic Interaction of S-ketamine, Morphine, Hydromorphone and Buprenorphine

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Id: NCT05571176

Organisation Name: Helsinki University Central Hospital

Overal Status: Not yet recruiting

Start Date: January 2023

Last Update: October 7, 2022

Lead Sponsor: Elina Brinck

Brief Summary: S-ketamine is often administered as a part of multimodal analgesia to reduce postoperative pain and postoperative opioid consumption. Current data indicates that ketamine may be useful for patients with prior use of opioids whereas the benefit for opioid-naive patients is less clear. However, different opioids have variable pharmacokinetic characteristics. Therefore, it is important to evaluate S-ketamine's effect on the pharmacokinetics of opioids.

  • The Effect of S-ketamine on Pharmacokinetics of Morphine, Hydromorphone, and Buprenorphine

Total execution time in seconds: 0.20864796638489