Ketamine molecule:

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Ketamine Clinical Trials


Investigation of Intranasal Ketamine Related Changes in Attentional Brain Networks With Functional and Structural MRI: a Placebo Controlled, Randomized, Cross-over Trial


To see complete record on clinicaltrials.gov, please visit this link

Id: NCT05320120

Organisation Name: Medical University of Vienna

Overal Status: Not yet recruiting

Start Date: April 23, 2022

Last Update: April 11, 2022

Lead Sponsor: Rupert Lanzenberger

Brief Summary: Subanesthetic ketamine is currently used as a rapid-acting antidepressant. It is an antagonist of the N-methyl-d-aspartate (NMDA) receptor, but former results indicate that its action also depends on the noradrenaline system and the locus coeruleus (LC).

Based on this known impact of ketamine on the sympathetic nervous system the aim of this study is to investigate the effects of intranasal esketamine on LC related attentional brain networks in task based functional MRI, to relate those attention network changes to behavioural measures and to predict ketamine related attention network changes by brain structure.

Conditions:
  • Ketamine Treatment


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