Ketamine molecule:

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Ketamine Clinical Trials

The Effects of Subanesthetic S-ketamine on Postoperative Delirium and Cognitive Function in the Elderly Undergoing Non-cardiac Thoracic Surgery: a Protocol for Randomized, Double-blinded, placebo-and Positive-controlled, Non-inferiority Trial

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Id: NCT05242692

Organisation Name: Affiliated Cancer Hospital & Institute of Guangzhou Medical University

Overal Status: Recruiting

Start Date: March 10, 2022

Last Update: July 29, 2022

Lead Sponsor: Affiliated Cancer Hospital & Institute of Guangzhou Medical University

Brief Summary: Postoperative delirium (POD) is a common and distressing complication after thoracic surgery. S-ketamine has neuroprotective properties as a dissociative anesthetic. Emerging literature has indicated that S-ketamine can reduce cognitive impairment in depressed patients. However, the role of S-ketamine in preventing postoperative delirium is still unknown. Therefore, this study aims to evaluate the effect of intraoperatively prophylactic S-ketamine compared to dexmedetomidine on the incidence of postoperative delirium in elderly patients undergoing non-cardiac thoracic surgery.

  • Postoperative Delirium
  • Elderly Patients

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