Ketamine molecule:

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Ketamine Clinical Trials

Effect(s) of Esketamine Combined With Pregabalin on Postsurgical Pain in Spinal Cord Neoplasms Patients

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Id: NCT05096468

Organisation Name: Beijing Tiantan Hospital

Overal Status: Not yet recruiting

Start Date: November 1, 2021

Last Update: October 27, 2021

Lead Sponsor: Beijing Tiantan Hospital

Brief Summary: Postsurgical pain is now known to be one of the most common and difficult-to-treat complications of surgery. Persistent pain can significantly impair patients' quality of life, social functioning and contribute to excessive health care expenditures. It is worth noting that acute postoperative pain may play a vital role in central sensitization and up-regulation of pain receptors, factors implicated in the development of CPSP. Poorly perioperative pain management may increase the incidence of CPSP. According to previous studies, the incidence of postoperative pain among patients undergoing spinal surgery was nearly 40%. At the same time, perioperative pain management of patients undergoing spinal surgery has not been clearly. For the past few years, pregabalin and esketamine are becoming important roles in perioperative pain management, lots of studies have shown that these two analgesics might relieve postoperative pain. The aim of this study was to evaluate the analgesic effects of esketamine and pregabalin in combination after spinal cord neoplasms resection, so as to find a better way to help the patients undergoing spinal surgery keep away from the perioperative pain.

  • Esketamine
  • Pregabalin
  • Perioperative Complication
  • Neuropathic Pain
  • Neurosurgical Procedures
  • Acute Postoperative Pain
  • Spinal Cord Neoplasms

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