Ketamine molecule:

Image from PubChem

Ketamine Clinical Trials

Effect of S-ketamine on Cortical Spreading Depolarisation and Cerebral Metabolic Crisis in Patients With Severe Acute Brain Injury

To see complete record on, please visit this link

Id: NCT05095857

Organisation Name: Rigshospitalet, Denmark

Overal Status: Not yet recruiting

Start Date: December 1, 2021

Last Update: October 27, 2021

Lead Sponsor: Rigshospitalet, Denmark

Brief Summary: Cortical spreading depolarisations are pathological depolarisation waves that occur frequently after severe acute brain injury and has been associated with poor outcome. S-ketamine has been shown to inhibit cortical spreading depolarisations. The aim of the present study is to examine the efficacy and safety of using S-ketamine for treatment of patients with severe acute brain injury, as well as the feasibility of the trial design.

  • Subarachnoid Hemorrhage, Aneurysmal
  • Intracerebral Hemorrhage
  • Traumatic Brain Injury

Total execution time in seconds: 0.23869609832764