Ketamine molecule:

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Ketamine Clinical Trials

S-ketamine for Cortical Spreading Depolarisation in Patients With Severe Acute Brain Injury

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Id: NCT05095857

Organisation Name: Rigshospitalet, Denmark

Overal Status: Not yet recruiting

Start Date: March 1, 2022

Last Update: January 27, 2022

Lead Sponsor: Rigshospitalet, Denmark

Brief Summary: Cortical spreading depolarisations are pathological depolarisation waves that occur frequently after severe acute brain injury and has been associated with poor outcome. S-ketamine has been shown to inhibit cortical spreading depolarisations. The aim of the present study is to examine the efficacy and safety of using S-ketamine for treatment of patients with severe acute brain injury, as well as the feasibility of the trial design.

  • Subarachnoid Hemorrhage, Aneurysmal
  • Intracerebral Hemorrhage
  • Traumatic Brain Injury

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