Ketamine molecule:

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Ketamine Clinical Trials

Investigating Glutamate and Opioid Mechanisms of Antidepressant Response to Ketamine

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Id: NCT04977674

Organisation Name: King's College London

Overal Status: Not yet recruiting

Start Date: August 2021

Last Update: July 27, 2021

Lead Sponsor: King's College London

Brief Summary: The overarching aim of this research is to determine the acute effects of ketamine on brain glutamate, functional connectivity and cerebral blood flow in treatment-resistant depression, explore whether the effects are attenuated by the opioid receptor antagonist naltrexone and relate these findings to antidepressant response.

  • Depressive Disorder, Treatment-Resistant

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