Ketamine molecule:

Image from PubChem

Ketamine Clinical Trials

Analgesic Effects of Low-dose S-ketamine in Patients Undergoing Major Spine Fusion Surgery: A Double-blinded, Randomized Controlled Trial

To see complete record on, please visit this link

Id: NCT04964219

Organisation Name: Peking University First Hospital

Overal Status: Recruiting

Start Date: February 8, 2022

Last Update: April 26, 2022

Lead Sponsor: Peking University First Hospital

Brief Summary: Despite opioid-based multimodal analgesia, moderate-to-severe pain remains a big problem in patients following multi-segment spinal fusion. As a N-methyl-D-aspartate receptor antagonist, S-ketamine has prominent analgesic effects through activating receptors both in the brain and in the spinal cord, inhibiting the excitatory postsynaptic potential, and thus blunting nociception transmission.

This randomized controlled trial is designed to investigate whether perioperative S-ketamine infusion can decrease pain intensity after major spine fusion surgery.

  • S-ketamine
  • Postoperative Analgesia
  • Spine Fusion

Total execution time in seconds: 0.19718194007874