Ketamine molecule:

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Ketamine Clinical Trials


Analgesic Effects of Low-dose S-ketamine in Patients Undergoing Major Spine Fusion Surgery: A Double-blinded, Randomized Controlled Trial


To see complete record on clinicaltrials.gov, please visit this link

Id: NCT04964219

Organisation Name: Peking University First Hospital

Overal Status: Not yet recruiting

Start Date: September 2021

Last Update: July 22, 2021

Lead Sponsor: Peking University First Hospital

Brief Summary: Despite opioid-based multimodal analgesia, moderate-to-severe pain remains a big problem in patients following multi-segment spinal fusion. As a N-methyl-D-aspartate receptor antagonist, S-ketamine has prominent analgesic effects through activating receptors both in the brain and in the spinal cord, inhibiting the excitatory postsynaptic potential, and thus blunting nociception transmission.

This randomized controlled trial is designed to investigate whether perioperative S-ketamine infusion can decrease pain intensity after major spine fusion surgery.

Conditions:
  • S-ketamine
  • Postoperative Analgesia
  • Spine Fusion


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