Ketamine molecule:

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Ketamine Clinical Trials

Adding Trauma-focused Psychotherapy to Ketamine Treatment for Chronic PTSD: A Pilot Study

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Id: NCT04889664

Organisation Name: Icahn School of Medicine at Mount Sinai

Overal Status: Recruiting

Start Date: June 4, 2021

Last Update: August 9, 2022

Lead Sponsor: Icahn School of Medicine at Mount Sinai

Brief Summary: The current project will evaluate the efficacy of adding Written Exposure Therapy (WET) to a course of repeated IV ketamine infusions in prolonging PTSD symptom improvement/time to loss of response in patients with chronic PTSD). WET is a brief, 5-session evidence-based written trauma-focused therapy without in between-session assignments, with demonstrated efficacy and low dropout rates in patients with PTSD. WET will be administered to all eligible participants; the first WET sessions will be interleaved with the last two ketamine infusions to take advantage of a window of increased neuroplasticity potentially induced by repeated ketamine infusions. WET will be administered on different days as the ketamine infusions.

  • PTSD

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