Ketamine molecule:

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Ketamine Clinical Trials

Effect of Low-dose Esketamine on Postoperative Depression in Patients With Breast Cancer

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Id: NCT04850937

Organisation Name: Yangzhou University

Overal Status: Completed

Start Date: February 10, 2021

Last Update: July 28, 2022

Lead Sponsor: Yangzhou University

Brief Summary: esketamine is an optical isomer of ketamine. Compared with ketamine, esketamine has the characteristics of higher effective value, stronger receptor affinity, less adverse reactions of nervous system, and pharmacokinetics is controllable.

Domestic and foreign studies have focused on the therapeutic effect of esketamine on major depression, but less attention has been paid to perioperative depression.This study intends to explore the effect of small doses of esketamine on patients with breast cancer.Postoperative depression and pain are observed.

  • Depression

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