Ketamine molecule:

Image from PubChem

Ketamine Clinical Trials

Comparing the Effect of Ketamine and Magnesium Sulfate Gargling With Placebo on Post-operative Sore Throat: A Randomized Controlled Trial

To see complete record on, please visit this link

Id: NCT04705948

Organisation Name: University Tunis El Manar

Overal Status: Completed

Start Date: October 7, 2020

Last Update: May 11, 2021

Lead Sponsor: University Tunis El Manar

Brief Summary: A prospective randomized double-blind study including patients ASA I-II, aged more than 18 years undergoing surgery under general anesthesia (GA) and endotracheal intubation. Patients were randomized allocated into 2 groups: ketamine group received ketamine gargle (0.5 mg/kg up to 30 ml dextrose water) and magnesium group received magnesium sulfate gargle (20 mg/kg up to 30 mL dextrose water ) 15 minutes before the operation.

Our primary outcome is sore throat and the secondary judging criteria are cough, dysphonia and satisfaction. A standardized anesthesia protocol was followed for all patients. After extubation, the patients were asked to grade POST, hoarseness, and cough at 15 min, 1h, and 24 h.

  • Postoperative Complications

Total execution time in seconds: 0.30808806419373