Ketamine molecule:

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Ketamine Clinical Trials

IM Ketamine vs Midazolam for Suicidal ER Patients

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Id: NCT04640636

Organisation Name: New York State Psychiatric Institute

Overal Status: Recruiting

Start Date: January 2, 2021

Last Update: March 10, 2022

Lead Sponsor: New York State Psychiatric Institute

Brief Summary: Rising US suicide rates and the increased risk of suicide among persons who visit an emergency department (ED) for suicidality make the ED an important site for interventions to prevent suicide. There is no approved treatment for rapid relief of suicidal thoughts although clinical trials, including ours, show relief of suicidal thoughts within hours of treatment with inexpensive, generic, sub-anesthetic ketamine. We propose a clinical trial of intramuscular ketamine in depressed ED patients with high-risk suicidality, which if successful would support a novel, easy-to-use, scalable intervention for busy emergency clinicians to implement.

  • Depression, Unipolar
  • Depression, Bipolar
  • Suicidal Ideation

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