Ketamine molecule:

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Ketamine Clinical Trials

Double-Blind Randomized Controlled Trial of Acute-Course of Ketamine Versus Midazolam for Recurrence of Suicidality in Adolescents

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Id: NCT04592809

Organisation Name: University of Texas Southwestern Medical Center

Overal Status: Recruiting

Start Date: October 3, 2022

Last Update: November 8, 2022

Lead Sponsor: University of Texas Southwestern Medical Center

Brief Summary: This project aims to examine the efficacy of ketamine, a rapidly acting medication shown to decrease suicidality in adults in as short as hours or days, as opposed to weeks.

The study design is a double-blind, randomized, active-control trial of adolescents (ages 13-18 years) with recent suicidal behaviors (suicide attempt or increased suicidal ideation). All participants must be receiving standard of care treatment which may range broadly from both outpatient and inpatient programs which include clinically indicated psychosocial and/or psychopharmacological treatments. Ketamine/midazolam treatment will occur twice weekly during the first two weeks of the study, followed by weekly assessments through week 12.

  • Suicide, Attempted
  • Suicide and Depression
  • Suicide Threat

Total execution time in seconds: 0.42768406867981