Ketamine molecule:

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Ketamine Clinical Trials

A Multicenter Study of the Efficacy and Safety of Esketamine for Analgesia During

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Id: NCT04548973

Organisation Name: Women's Hospital School Of Medicine Zhejiang University

Overal Status: Recruiting

Start Date: January 1, 2021

Last Update: January 27, 2022

Lead Sponsor: Women's Hospital School Of Medicine Zhejiang University

Brief Summary: This study proposed applying intravenous Esketamine to cesarean section in parturient, detecting the plasma concentration of Esketamine in maternal blood, neonatal umbilical venous blood and umbilical arterial blood when the baby is delivered ketamine blood drug concentration, observing vital signs, adverse visual analog pain score (VAS), and sedation score (Ramsay) in parturient, neonatal Apgar score 1, 5 to 10 minutes after birth, the umbilical arterial blood gas and neurobehavioral scores (NBNA) 2, 24 hours after the birth. This study aims to address placental transfer, metabolism and analgesic and sedative effects in neonates and parturients of Esketamine so as to explore the feasibility, efficacy and safety of Esketamine as adjuvant medication for cesarean section.

  • Fetal or Neonatal Effect of Damage to Placenta From Caesarean Section

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