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Ketamine Clinical Trials

Incidence of Emergence Delirium in the PACU: Prospective Observational Trial

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Id: NCT04531020

Organisation Name: Brno University Hospital

Overal Status: Recruiting

Start Date: October 1, 2020

Last Update: October 5, 2020

Lead Sponsor: Brno University Hospital

Brief Summary: Emergence delirium (ED) is serious complication in the postoperative period in paediatric anaesthesia, reported incidence is 20-60%. It is characterized by psychomotor and perception disorder with excitation of paediatric patients. Emergence delirium has impact on morbidity and even on mortality of paediatric patients in the postoperative period.

The potential risk factors for ED development include sevoflurane, which is the dominant anaesthetic agent used in the paediatric patients, and which is actually the only inhalation agent used for inhalation anaesthesia induction. The incidence of ED is higher in postoperative period, for example in the Post-anaesthesia Care Unit - PACU. Patients with ED are at higher risk of psychomotor anxiety, agitation, unintentional extraction of intravenous cannula, and nausea and vomiting. For the therapy of ED propofol, midazolam and eventually ketamine in a reduced dosage are used.

  • Emergence Delirium

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