Ketamine molecule:

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Ketamine Clinical Trials

A Practical, Pilot, Randomized, Controlled Trial of Valproate Alone or in Combination With Quetiapine for Severe COVID-19 Pneumonia With Agitated Delirium

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Id: NCT04513314

Organisation Name: University of Miami

Overal Status: Not yet recruiting

Start Date: November 1, 2021

Last Update: November 10, 2020

Lead Sponsor: University of Miami

Brief Summary: The primary purpose of this research is to determine whether Valproate alone, and in combination with Quetiapine, lowers confusion and agitation in persons with severe Corona Virus Disease (COVID)19 pneumonia during weaning from the breathing machine (ventilator). Though Valproate and Quetiapine are often given to persons with severe confusion with agitation, the purpose of this small research study is specifically for: a) persons infected with COVID 2019 on a ventilator whose agitation is not responding to the usual medications (like dexmedetomidine), and b) to reduce the time persons are treated with dexmedetomidine, which requires continuous close monitoring in an ICU.

  • Covid19
  • Hyperactive Delirium
  • Pneumonia, Viral

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