Ketamine molecule:

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Ketamine Clinical Trials


Department of Anaesthesiology


To see complete record on clinicaltrials.gov, please visit this link

Id: NCT04491786

Organisation Name: Gia Dinh People Hospital

Overal Status: Not yet recruiting

Start Date: August 1, 2020

Last Update: July 31, 2020

Lead Sponsor: Gia Dinh People Hospital

Brief Summary: The acute pain after spinal surgery is serious. The most pain is during 24 hours after surgery. The multimodal therapy is a method which is applied to treat the postoperative pain.

Morphine is main analgesic to treat postoperative pain. However, some the side-effects can occur to patients and there are associate with dosage. So, some analgesics usually combinate with morphine to postoperative analgesia, include gabapentin, celecoxib, ketamine, ...

Nefopam is a central analgesic. There are effect prevent hyperalgesia. The effect of the combination of gabapentin with nefopam to postoperative analgesia in spinal surgery hasn't been reported yet.

The gabapentin oral with 600 mg combine with continuously intravenous nefopam with 65 µg/kg/hour during 24 hours after spinal surgery whether to increase the effect of postoperative analgesia.

The investigators hypothesized that the gabapentin oral with 600 mg combine with continuously intravenous nefopam with 65 µg/kg/hour during 24 hours after spinal surgery can decrease 40% of the consumption of morphine during 24 hours.

Conditions:
  • Spinal Fusion


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