Ketamine molecule:

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Ketamine Clinical Trials

Comparison of CRP Levels, Neutrophil Count, and Clinical Outcomes of Low Dose Ketamine Between at Anesthesia Induction and at the End of Surgery in Patients Undergo Elective Laparotomy

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Id: NCT04462094

Organisation Name: Udayana University

Overal Status: Completed

Start Date: July 27, 2020

Last Update: November 12, 2020

Lead Sponsor: Udayana University

Brief Summary: The effects of anesthesia and surgery can lead to stress responses that result in hormonal and metabolic changes in the body. The immune system and the nervous system communicate both ways, and it was found that nociception and proinflammatory cytokines play a joint regulatory role, i.e., increased production of proinflammatory cytokines can worsen the pain. Major surgery can trigger the release of cytokines such as IL-1, IL-6, and TNF-α.

  • General Anesthesia
  • Laparotomy
  • Inflammation

Total execution time in seconds: 0.20093107223511