Ketamine molecule:

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Ketamine Clinical Trials

Efficacy and Safety of Continuous Infusion of Ketamine in Pediatric Intensive Care Unit (KISS Study)

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Id: NCT04427605

Organisation Name: Azienda Ospedaliera di Padova

Overal Status: Completed

Start Date: April 1, 2019

Last Update: February 15, 2022

Lead Sponsor: Azienda Ospedaliera di Padova

Brief Summary: This study, prospectively evaluate the efficacy and safety of ketamine administered in continuous infusion lasted more than 12 hours in children admitted to Pediatric Intensive Care Unit of Padova. This drug may be used as adopted as adopted as adjuvant to analgesia and sedation or as adjuvant to bronchospasm therapy. The investigators evaluated efficacy considering the sparing of other analgesics and sedatives and the level of sedation after ketamine infusion for the first use and the sparing of other bronchospasm drugs sedative dosage for the second use. To evaluate safety the investigators considered the presence of adverse effects and onset of withdrawal and delirium syndrome. The study will included al least 55 pediatric patients < 18 years and mechanically ventilated.

  • Analgesia
  • Ketamine Toxicity
  • Bronchospasm
  • Sedation Complication

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