Ketamine molecule:

Image from PubChem

Ketamine Clinical Trials

Paravertebral Block Versus Simultaneous Ketamine and Lidocaine Infusions for Pain Management in Rib Fracture Patients

To see complete record on, please visit this link

Id: NCT04413799

Organisation Name: George Washington University

Overal Status: Recruiting

Start Date: September 1, 2020

Last Update: January 4, 2023

Lead Sponsor: George Washington University

Brief Summary: Rib fractures are a common admission to the trauma service. The mainstay of treatment is pain control to improve respiratory effort in order to offset the risk of pneumonia and mechanical ventilation. In addition to standard pain control modalities, the investigator's institution utilizes paravertebral blocks as well as lidocaine and ketamine infusions for pain control. The current standard of care for pain control is to begin with acetaminophen, ibuprofen or celecoxib and opioids with the addition of paravertebral blocks as needed. In certain situations, a paravertebral block is contraindicated, and pain control is relegated to lidocaine and ketamine infusion. The use of lidocaine infusion alone and ketamine infusion alone for pain control has been studied and has been shown to be safe. However, concurrent use of these two medications to control rib fracture pain is relatively new and the efficacy compared to paravertebral block is not known. The goal of the study is to show non-inferiority of simultaneous lidocaine and ketamine infusions versus paravertebral blocks.

  • Rib Fractures
  • Rib Trauma
  • Rib Fracture Multiple
  • Pain, Acute

Total execution time in seconds: 0.21359610557556