Ketamine Clinical Trials
Opioid Free Anaesthesia vs Opioid Based Anesthesia in Cleft Lip, Palate ,Alveolus Surgery.
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Organisation Name: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Overal Status: Unknown status
Start Date: September 4, 2019
Last Update: September 9, 2019
Lead Sponsor: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Brief Summary: Peri-operative opioid administration has long been one of the three pillars of 'balanced anaesthesia',over the span of just a few years,opioids were widely used in perioperative analgesia because of pain as the fifth vital sign.However, opioid administration is not without concern and is associated with many side-effects such as constipation, urinary retention, respiratory depression and postoperative nausea and vomiting .Cleft lip,palate,alveolus are common craniofacial abnormalities and usually require surgical repair.These patients have risks for various perioperative complications due to their young age and craniofacial abnormalities.Conditions
This study was designed to compare the effects of opioid based anesthesia（OBA） and opioid free anesthesia(OFA )on perioperative complications in patients with in cleft lip,palate,alveolus surgery, including respiratory depression, postoperative nausea and vomiting, hemodynamic effects, etc.
Total execution time in seconds: 0.20737099647522