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Ketamine Clinical Trials

The Effect of Ketamine Between Generations in Operation Theater- Focus on Electroencephalogram Changes

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Id: NCT03679390

Organisation Name: National Taiwan University Hospital

Overal Status: Terminated

Start Date: March 1, 2017

Last Update: July 6, 2021

Lead Sponsor: National Taiwan University Hospital

Brief Summary: The electroencephalography (EEG) is a noninvasive medical technique for monitoring and recording the electrical activity of brain. The Hilbert-Huang Transformation (HHT) was proposed to decompose EEG signal into intrinsic mode functions (IMF). HHT can obtain instantaneous frequency data and work well for nonstationary and nonlinear data. We applied this method in perioperative EEG signal analysis in order to find the energy shift and quantify the energy change during general anesthesia. Ketamine was a depolarized sedative which was wildly used in anesthesia. We are trying to find the energy change after ketamine injection, and the interaction between different oscillations in EEG. The whole brain mapping for ketamine and other sedatives interaction is the next step.

  • Electroencephalogram
  • Consciousness, Loss of

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