Ketamine molecule:

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Ketamine Clinical Trials

Ketamine's Efficiency in the Treatment of Chronic Pain With an Added Inflammatory Component Exploring the Kynurenin Pathway. A Randomized, Double Blind, Placebo-controlled Trial

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Id: NCT03513822

Organisation Name: Redar

Overal Status: Unknown status

Start Date: February 16, 2018

Last Update: May 2, 2018

Lead Sponsor: Redar

Brief Summary: The kynurenine pathway is involved in hyperalgesia. This pathway is activated by inflammation. Ketamine would interact with the kynurenine pathway and inflammation. Our working hypotheses are: the clinical effects of ketamine on neuropathic pain are greater in the presence of systemic inflammation and the mechanism of action involves an interaction on the kynurenine pathway.

Study design: Interventional randomized placebo-controlled clinical trial.

Main goals:

To show a better clinical efficacy of ketamine in chronic pain in patients with an inflammatory component.
Explore the anti-inflammatory activity of ketamine through the Kynurenine pathway.

  • Neuralgia
  • Chronic Pain
  • Inflammation

Total execution time in seconds: 0.97773289680481