Ketamine molecule:

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Ketamine Clinical Trials

Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response

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Id: NCT03367533

Organisation Name: Yale University

Overal Status: Recruiting

Start Date: November 29, 2018

Last Update: August 10, 2022

Lead Sponsor: Yale University

Brief Summary: The proposed study will assess the combined effect of perampanel and ketamine on the anti-depressant response in individuals with treatment resistant depression. The purpose of this study is to test the hypothesis that stimulation of Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid receptors (AMPAR) is critical to the anti-depressant response of ketamine.

  • Depressive Disorder, Major
  • Bipolar Disorder
  • Post Traumatic Stress Disorder

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