Ketamine molecule:

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Ketamine Clinical Trials

Electroencephalographic Effects of Ketamine During Isoflurane Maintenance and Recovery

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Id: NCT03290495

Organisation Name: Minia University

Overal Status: Completed

Start Date: September 30, 2017

Last Update: November 28, 2017

Lead Sponsor: Minia University

Brief Summary: Ketamine effect on isoflurane anesthesia This study is designed to study the effect of ketamine on isoflurane anesthesia. As both drugs are hypnotic and are used to cause sleep during surgery and other painful procedures, it was long believed that the actions of two drugs add to each other. For example if a man received both drugs, this man will become awake from anesthesia much later than if this man was given either of them alone.

However recent studies showed that this is not the case and ketamine can cause fast recovery from hypnotic effects of isoflurane. This was confirmed in animals.

The aim of current study is to investigate if this effect applies for humans, using a state of art brain monitoring device in wide use nowadays called BIS or bispectral index. This device can also shed some light on how ketamine can cause, if any, fast recovery from isoflurane anesthesia. Simply, by studying electrical wave coming from brain to head skin.

  • Post-anesthesia Recovery

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