Ketamine molecule:

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Ketamine Clinical Trials

A Prospective Randomized Controlled Trial of Electroconvulsive Therapy With Ketamine Anesthesia (Standard Therapy) and High Intensity Ketamine With Electroconvulsive Therapy Rescue for Treatment-Resistant Depression - EAST HIKER Trial

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Id: NCT03272698

Organisation Name: University of Saskatchewan

Overal Status: Recruiting

Start Date: September 1, 2017

Last Update: November 1, 2022

Lead Sponsor: University of Saskatchewan

Brief Summary: To determine if an high intensity ketamine with ECT rescue (HIKER) approach for treatment resistant depression will: 1) reduce patient suffering by hastening disease remission, 2) have fewer side effects, 3) reduce the need for ECT, and 4) be preferred by most patients. Half of participants will be randomized to the HIKER arm and receive high intensity ketamine treatment for eight consecutive days, and the other half will be assigned to the ECT with ketamine anesthesia (EAST) arm and receive 8 ECT treatments (2-3 treatment/week)

  • Treatment Resistant Depression
  • Ketamine

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