Ketamine molecule:

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Ketamine Clinical Trials

Effect of Low-dose Ketamine on Postoperative Depressive Symptom in Patients Undergoing Intracranial Tumor Resection (PASSION)

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Id: NCT03086148

Organisation Name: Beijing Tiantan Hospital

Overal Status: Completed

Start Date: July 5, 2017

Last Update: July 7, 2020

Lead Sponsor: Beijing Tiantan Hospital

Brief Summary: Perioperative depression symptom (PDS) is one of the common mental comorbidity, and influences the clinical outcomes and prognosis. However, there is no rapid acting treatment to deal with it during the limited hospital stay. This study aims to determine whether ketamine could improve the depressive symptom of peirioperative patients. It will also examine the safety for administrating ketamine as an antidepressant intraoperatively. Meanwhile, it will show if ketamine could improve anxiety, postoperative pain or delirium. This trial also will bring great concerns on patients with perioperative mental health and explore the measures to improve their psycho-related prognosis.

  • Ketamine; Depressive Symptom; Neurosurgery; Perioperative Period

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