Ketamine molecule:

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Ketamine Clinical Trials

Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy: a Pilot Study

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Id: NCT02987985

Organisation Name: University of Saskatchewan

Overal Status: Completed

Start Date: October 15, 2017

Last Update: August 10, 2021

Lead Sponsor: University of Saskatchewan

Brief Summary: The objective of this trial is to determine whether an opioid-free general anesthetic (OFA) technique utilizing ketamine, dexmedetomidine, lidocaine, and gabapentin can help reduce postoperative respiratory depression in the post-anesthesia care unit and ward in children with sleep-disordered breathing undergoing tonsillectomy when compared with traditional opioid-containing techniques. It is expected that this OFA regimen will have a measurable reduction on postoperative respiratory depression in children with sleep-disordered breathing.

  • Anesthesia
  • General Anesthesia
  • Analgesics, Opioid
  • Postoperative Complications
  • Pathologic Processes
  • Physiologic Effects of Drugs
  • Narcotics
  • Analgesics
  • Sleep Disordered Breathing
  • Obstructive Sleep Apnea of Child
  • Tonsillectomy
  • Respiratory Depression
  • Dexmedetomidine
  • Ketamine
  • Lidocaine
  • Gabapentin
  • Pulse Oximetry

Total execution time in seconds: 0.25285911560059