Ketamine molecule:

Image from PubChem

Ketamine Clinical Trials


NMDA Antagonists and Steroids for the Prevention of Persisting Post-Surgical Pain After Thoracoscopic Surgeries: A Randomized Controlled, Factorial Design, International, Multicentre Pilot Study


To see complete record on clinicaltrials.gov, please visit this link

Id: NCT02950233

Organisation Name: Population Health Research Institute

Overal Status: Terminated

Start Date: May 4, 2017

Last Update: January 18, 2020

Lead Sponsor: Population Health Research Institute

Brief Summary: The objective of the PAIN-STOP trial is to assess the feasibility of a larger randomized controlled trial (RCT) evaluating NMDA antagonists and IV steroids, as compared to placebo, in decreasing the chances of clinically significant persistent post-surgical pain (PPSP) after video assisted thoracoscopic surgeries (VATS). This is a multi-centre randomized, controlled clinical trial with a 2 x 2 factorial design. The pilot phase of the trial will recruit 48 patients and follow them for 3 months. Patients will be randomized to one of four groups: 1) NMDA active + Steroid placebo; 2) Steroid active + NMDA placebo; 3) NMDA active + Steroid active; 4) NMDA placebo + Steroid placebo.

Conditions:
  • Pain, Postoperative


Total execution time in seconds: 2.0512239933014