Ketamine molecule:

Image from PubChem

Ketamine Clinical Trials

A Comparison of Midazolam or Haloperidol Premedication Versus Placebo for Reducing Ketamine Induced Agitation After Adult Procedural Sedation in the Emergency Department

To see complete record on, please visit this link

Id: NCT02909465

Organisation Name: Tehran University of Medical Sciences

Overal Status: Completed

Start Date: July 2016

Last Update: November 7, 2017

Lead Sponsor: Tehran University of Medical Sciences

Brief Summary: Ketamine is the cornerstone of procedural sedation in emergency department but ketamine induced agitation has limited its usage by many physicians. As a solution, some propose using midazolam or haloperidol before ketamine injection. In this randomized double blind clinical trial, patients who are eligible for sedation by ketamine are allocated in 3 groups. In first group, the patients will receive 0.05 mg/kg midazolam, in second group 5 mg of haloperidol and in 3rd group a placebo five minutes before receiving the sedative dose of ketamine (1 mg/kg). The patients are assessed for agitation during and after the procedure the clinician's satisfaction with sedation instrument is evaluated after the procedure.

  • Ketamine Induced Agitation

Total execution time in seconds: 0.21845698356628