Ketamine molecule:

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Ketamine Clinical Trials

Prehospital Analgesia With Intra-Nasal Ketamine

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Id: NCT02753114

Organisation Name: University of British Columbia

Overal Status: Completed

Start Date: November 6, 2017

Last Update: October 22, 2018

Lead Sponsor: University of British Columbia

Brief Summary: Acute painful conditions make-up a large proportion of pre-hospital transports in British Columbia (BC) yet Basic Life Support (BLS) paramedics have limited options to provide analgesia and therefore adequate and timely pain relief is often significantly delayed.

Inhaled nitrous oxide is commonly used as a pre-hospital analgesic and is considered "usual care" for pre-hospital providers in BC, but its utility in severe pain is uncertain. Moreover, nitrous oxide is limited in its effectiveness by a short duration of action, nausea, vomiting, and the necessity for patient cooperation.

IN Ketamine has been shown to provide rapid, easily-administered, and well-tolerated analgesia in many settings. The investigators believe that the addition of IN ketamine to usual care with nitrous oxide inhalation for adults experiencing moderate to severe intensity acute pain in the pre-hospital setting will result in improved pain severity, improved patient-reported comfort, and improved patient satisfaction.

  • Pain
  • Acute Pain

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