Ketamine molecule:

Image from PubChem

Ketamine Clinical Trials

The CHECK Trial: A Comparison of Headache Treatment in the Emergency Department: Compazine Versus Ketamine. A Multi-Center, Randomized, Double-Blind, Clinical Control Trial

To see complete record on, please visit this link

Id: NCT02735343

Organisation Name: Mike O'Callaghan Military Hospital

Overal Status: Terminated

Start Date: August 2016

Last Update: June 2, 2017

Lead Sponsor: Mike O'Callaghan Military Hospital

Brief Summary: Investigators are comparing Ketamine to prochlorperazinecompazine for benign headaches in the ED. Subjects will be randomized into 1 of 2 groups. Group 1 will receive standard treatment of prochlorperazinecompazine 10 mg IV along with diphenhydramine 25 mg IV. Group 2 (research arm) will receive Ketamine 0.3 mg/kg along with ondansetron 4 mg IV. Subjects will be seen at 15, 30, 45, and 60 minutes post-intervention to obtain Heart Rate, Blood Pressure, Headache severity, Nausea severity, Vomiting severity, Anxiety severity, and Restlessness severity. At 24-48 hours post intervention we will contact subjects and assess their pain and assess their satisfaction with their migraine pain management as part of this study. Subjects' participation will last up to 48 hours post headache.

  • Headache

Total execution time in seconds: 0.20894002914429