Ketamine molecule:

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Ketamine Clinical Trials

A Phase II, Randomised, Double-blind, Placebo- Controlled, Multi-site, Parallel Group Clinical Trial to Examine Ketamine as a Pharmacological Treatment for Alcohol Dependence in an Alcohol Dependent Population

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Id: NCT02649231

Organisation Name: University College, London

Overal Status: Completed

Start Date: October 2016

Last Update: October 5, 2021

Lead Sponsor: University College, London

Brief Summary: 96 recently detoxified alcoholics will be randomized to receive either 3 sessions ketamine (0.8 mg/kg IV over 45 minutes) or placebo plus manualised psychological therapy, or 3 sessions of ketamine or placebo plus simple psychoeducation. Patients will be assessed at 3 and 6 months on a range of psychological and biological variables. Primary endpoints will be % days abstinent at 6 months and relapse rates at 6 months. Secondary endpoints include depressive symptoms, craving, quality of life.

  • Primary Alcohol Use Disorder

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