Ketamine molecule:

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Ketamine Clinical Trials

Pupillary Diameter Variation After Standardized Tetanic Stimulations of Incremental Intensities in Patients Under Ketamine Sedation

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Id: NCT02648412

Organisation Name: Hôpital Armand Trousseau

Overal Status: Completed

Start Date: April 2012

Last Update: December 22, 2016

Lead Sponsor: Pr Isabelle CONSTANT

Brief Summary: The aim of the study was to describe the relationship between the intensity of a standardized tetanic stimulation and the associated reflex pupillary dilation in patients under ketamine sedation.

After an intravenous bolus of 1 mg/kg of ketamine, tetanic stimulations were performed every minute at increasing intensities of 10, 20, 30, 40 and 60 milliamps (similar to the stimulations of neuromuscular blocking agents monitoring). Pupillary diameter was measured before and after each stimulation.

  • Pain
  • Anesthesia

Total execution time in seconds: 1.4785640239716