Ketamine molecule:

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Ketamine Clinical Trials

Spreading Depolarization and Ketamine Suppression

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Id: NCT02501941

Organisation Name: University of New Mexico

Overal Status: Completed

Start Date: July 2015

Last Update: October 25, 2017

Lead Sponsor: University of New Mexico

Brief Summary: Hypothesis: Cortical spreading depolarizations are inhibited by the NMDA receptor antagonist Ketamine Aim 1: To demonstrate, in a group of patients with acute severe brain injury requiring surgery including traumatic brain injury and aneurysmal subarachnoid hemorrhage, whether use of continuous infusion of ketamine decreases frequency of occurrence of cortical spreading depolarizations.

  • Cortical Spreading Depolarization
  • Cortical Spreading Depression
  • Subarachoid Hemorrhage
  • Traumatic Brain Injury

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