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Ketamine Clinical Trials

Comparison Between Ketamine and Tramadol for Pain Management After Major Upper Abdominal Surgery

To see complete record on clinicaltrials.gov, please visit this link

Id: NCT02499341

Organisation Name: Attikon Hospital

Overal Status: Completed

Start Date: July 2011

Last Update: July 16, 2015

Lead Sponsor: Attikon Hospital

Brief Summary: The purpose of the study is the comparison between ketamine and tramadol, regarding the analgesia quality and efficiency, in patients receiving Patient Controlled Analgesia (PCA) morphine, after major upper abdominal surgeries such as hepatectomies, gastrectomies, Whipple procedures and peripheral pancreatectomies. The goal is to bring out an improved analgesia scheme, which can be applied to the clinical work and refine the analgesia provided for major procedures which require increased postoperative opioids doses. In the study, half of patients will receive continuous intravenous infusion of tramadol and Patient Controlled Analgesia morphine and the other half will receive continuous intravenous infusion of ketamine and Patient Controlled Analgesia morphine postoperatively after major upper abdominal surgery. The successful combination of different drugs targets at the improvement of the analgesia provided, the reduction of complications and the exploitation of the pharmacodynamic properties of each drug.

• Postoperative Pain