Ketamine molecule:

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Ketamine Clinical Trials

Intrathecally Administered Ketamine, Dexmedetomidine, and Their Combination With Bupivacaine for Postoperative Analgesia in Major Abdominal Cancer Surgery

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Id: NCT02455609

Organisation Name: Assiut University

Overal Status: Unknown status

Start Date: March 2015

Last Update: May 28, 2015

Lead Sponsor: Assiut University

Brief Summary: Currently, opioids are widely used for pain relief, but they often provide sub-optimal analgesia with occasional serious side effects. Preservative-free ketamine hydrochloride was introduced as a spinal anesthetic more than twenty years ago and found to have advantages over local anesthetics. Intrathecal dexmedetomidine provides an analgesic effect in postoperative pain without severe sedation. The objectives of this study were to compare the efficacy and safety of intrathecally administered dexmedetomidine, ketamine, or their combination when added to bupivacaine for postoperative analgesia in major abdominal cancer surgery.

  • Therapy
  • Pain Management

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