Ketamine molecule:

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Ketamine Clinical Trials

Low Dose Ketamine Prevent the Postoperative Cognitive Dysfunction in Aged Patients Underwent Orthopaedic Surgery,a Randomized Control Double Blinded Multicenter Clinical Trail

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Id: NCT02220400

Organisation Name: RenJi Hospital

Overal Status: Unknown status

Start Date: September 2014

Last Update: August 19, 2014

Lead Sponsor: RenJi Hospital

Brief Summary: Previous study demonstrated that neuroinflammation induced by surgery is the main cause of the postoperative cognitive dysfunction. As an agonist of NMDA receptor, ketamine is proved to be an anti-inflammation agent. In present study investigators hypothesized that low dose ketamine would prevent the cognition decline after orthopedic surgery in aged patients.

  • Necrosis of Femoral Head
  • Knee Osteoarthritis

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