Ketamine molecule:

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Ketamine Clinical Trials

Ketamine Patient-Controlled Analgesia for Acute Pain in Native Airway Multiple and Orthopedic Trauma Patients: A Randomized, Active Comparator, Blinded Trial

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Id: NCT02062879

Organisation Name: University of Cincinnati

Overal Status: Terminated

Start Date: April 2014

Last Update: September 21, 2017

Lead Sponsor: University of Cincinnati

Brief Summary: This study will compare ketamine and hydromorphone as alternative patient-controlled interventions for trauma-related pain. Patients receiving ketamine PCA are expected to require less total and breakthrough opioid and to have similar or improved objective pain scores. Patients receiving ketamine are also expected to have shorter duration of supplemental oxygen requirement, fewer episodes of oxygen desaturation, improved pulmonary toilet, lower use of antiemetics, and shorter times to first bowel movement. Ketamine is further expected to be associated with decreased intensive care unit and hospital lengths of stay, faster time to maximum allowable ambulation, decreased opioid dosage at discharge, and lower report of chronic pain syndromes.

  • Acute Pain
  • Multiple Trauma
  • Fractures

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