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Ketamine Clinical Trials

Sub-dissociative Ketamine for the Management of Acute Pediatric Pain

To see complete record on clinicaltrials.gov, please visit this link

Id: NCT01951963

Organisation Name: HealthPartners Institute

Overal Status: Completed

Start Date: December 2012

Last Update: July 3, 2018

Lead Sponsor: HealthPartners Institute

Brief Summary: The proposed trial is a prospective, double blinded, randomized control trial with the primary aim of determining whether a single, sub-dissociative dose of ketamine will decrease the total narcotic requirements of pediatric patients requiring intravenous analgesia in an urban emergency department (ED) compared to a group of patients who receive morphine alone for pain management. Patients are randomized to receive either a single bolus of ketamine (0.3 mg/kg) or a single bolus of morphine (0.05mg/kg). All subsequent pain management will be accomplished using morphine. Patient, family member, and research staff pain scores will be recorded, until 3 hours post study medication administration. Family members are contacted via telephone 24 hours post-ED discharge, and again at 7 days post-hospital discharge, for evaluation via Post Hospitalization Behavior Questionnaire. Narcotic equivalents will be calculated for up to 3 hours post study medication administration and compared between the ketamine and morphine groups.

• Pain