Ketamine molecule:

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Ketamine Clinical Trials

Effectiveness of Atropine and Glycopyrrolate to Reduce Hyper Salivation With Ketamine Sedation

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Id: NCT01191398

Organisation Name: University of Texas Southwestern Medical Center

Overal Status: Completed

Start Date: June 2010

Last Update: April 16, 2014

Lead Sponsor: Craig J. Huang

Brief Summary: The purpose of this study is to determine if the antisialagogues (anti-salivary agents), Atropine and Glycopyrrolate, are effective in reducing hypersalivation when sedating patients with Ketamine for procedural sedation in the emergency department or abscess clinic. The investigators will measure salivary flow rate by collecting oral secretions by oral suctioning over a 30 minute time period starting with the administration of Ketamine. The investigators hypothesize that patients who receive either atropine or glycopyrrolate will have fewer oral secretions than patients who receive placebo.

  • Sialorrhea

Total execution time in seconds: 0.36482501029968