Ketamine molecule:

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Ketamine Clinical Trials

The Effectiveness of Small Doses of Ketamine With Morphine on Decreasing Pain Responses During Open Wound Care

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Id: NCT00701909

Organisation Name: University of California, San Francisco

Overal Status: Completed

Start Date: June 2008

Last Update: January 16, 2014

Lead Sponsor: University of California, San Francisco

Brief Summary: This is a randomized double-blind study to determine if the administration of a small-dose of ketamine (an anesthetic)added to morphine (an opioid) contributes to reducing pain intensity during open wound care procedure (WCP)in patients who have had a traumatic injury and are in an Intensive Care Unit. Patients will be randomized to receive morphine plus saline (a placebo) or morphine plus ketamine before the WCP. The second time the patient is scheduled for WCP (no less than 24 hours), patients will be crossed over to receive the treatment they did not receive the first time. It is hypothesized that patients who receive the combination of morphine and ketamine will have better pain control during the procedure than patients who just receive morphine.

  • Wound Care
  • Pain Intensity
  • Hyperalgesia
  • Nausea
  • Vomiting
  • Hallucinations

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