Ketamine molecule:

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Ketamine Clinical Trials

A Double-blind Randomised, Placebo-controlled Study of Adjunctive Ketamine Anaesthesia in ECT (Electroconvulsive Therapy)

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Id: NCT00680433

Organisation Name: Northside Clinic, Australia

Overal Status: Completed

Start Date: April 2008

Last Update: March 29, 2013

Lead Sponsor: Northside Clinic, Australia

Brief Summary: Research into the mechanisms underlying memory impairment in ECT suggests that its development may be prevented by the administration of certain medications at the time of ECT treatment. For example there are reasons to believe that ketamine, also used as an anaesthetic agent, may have such protective properties.

In this clinical study patients undergoing a course of ECT will be offered the opportunity to receive a small dose of ketamine (or a placebo) as part of their anaesthetic at the time of ECT treatment. Mood changes and any memory changes will be evaluated to see if the subjects who received ketamine had less memory side effects than those who did not, while still improving their depression.

  • Major Depressive Episode

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